SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08c3f63405d8c255be5ce3f1f0e1ccf5d16364bc5fbaab4fdd87efeb87cf3978' 
  AND token = 'lskS/ixrQppnWB7t3GlC7reOVl1qUzi5Lm0waeKt+Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}