SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88fc07c6c3b69600f748e90ef19b509e0a0aa4e57316e6102895b07cc980a28c' 
  AND token = '5gFP/cl/G+bM04PwxuhaHmVXSPEkIbgws9CugrB1pI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}