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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9294e4326745e833cbc931f1a090243f61570fc3ad46320fa0596703d287365a' 
  AND token = 'EPIqzbPpwNbOH5s2QtDkr68xp+m5jj/ePYdoVtuSsDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}