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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a10bba1fae02657d2fbbe1b9748b980da92f7c64a29d9d6cc3333fd4729e788' 
  AND token = 'rT4pJc7hT1oRYyzIgZP2HN1vAyf+zgzk8N8o8fCeAzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}