SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39d556ec2ccda5b429afc263cb3c9e3bf6a37607787fd7d107cccc3c79a5db3d' 
  AND token = 'T+EOdy2dhIiIhgFqZFi5oeXuUs6j9M2PRPyWyQI/uPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}