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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5bf6ad4d08f998aa0123adeaef36c86bd19f40e4ed5cb6e0156c27e84884361' 
  AND token = 'zwcYqktcSA3LQ/BRtu21CDVX19N0vQFLFt9MbSdF1fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}