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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0eadc4be253816b48b5ecc78cd03730a9db21ba7b1c4eb92fb90cac22eada152' 
  AND token = 'TqUjyeI9hUQ1sPRP7yLzSVmgPD5UUFO39VciqJyrfZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}