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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2f695a4350182cdf9741fb9b45805baa624dcf0991bd106a8be4c1497b65edc' 
  AND token = 'Ue3wQMb0/vh/x+MSJPQew6/kxFkC6UNoq5rypySFxHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}