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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '421c063b1c0b30e33650a61ccb9834623330f9ea3bff85591e5ac2272edbda9d' 
  AND token = '82g4wZVSvnZadtyQ+WMW5tgxGhLnGATnBE07NH01010=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}