SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cf55c8425ef9ef8ecb4d70d69a56c76981c639d4854501013cf8ac939f096a0' 
  AND token = 'vvbKXgQjF0E3e9XdnXrBDK4Ll8aKeiuHdZnl/29V8Gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}