SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '349e64f60e6294b8027229ba9dfe2feba3e2decdc09a49d83b312e5b38fca1d0' 
  AND token = 'i1oFb4DGUAHbpG6SugaMrFXZqz/YCxgaPA5vI7p27po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}