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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b05507dd564638ab2cda45b6f38566b8577a79f7151d13130f5581c02160a7' 
  AND token = '1IhwZDMCRgjcWGULcx3u32AqItApsf0rzY8e7Jb89Ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}