SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0eba1a48df42b842a56545f311695b51167129843ebdef0a2a74e5be9271b9b' 
  AND token = 'CPdtlIki1mTRyaSoSTxjjwWTonXd+R5cDb6FopYPD/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}