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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4dc1018233c1ee55c5e129e79f6889fa1a17cfecf4ec03350b4dc69d81be20c' 
  AND token = 'mPPKay0r6UOAtorD4PZCLoU7r+zUBsqJi6IqQzVsjbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}