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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2a03d5d56644f4851040f55fb4454ae023658a0c666793dd17e86826fe77813' 
  AND token = '+e2npNF2Ao0vmNGGj0Vcy/dGy6KwLCv1F/DJwZgkgDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}