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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff54a2371f6b54d363850322e2fffa7d31a83db90b4f9e0b0442acfebdab62a6' 
  AND token = 'THdxlJM/z+u0enOdZ93nwQAteAOA1QbBQOp64N37rOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}