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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376b5bf53dbb939343c14be59bc720da97097e9de81c5fbcde4729f4ebaa5014' 
  AND token = '2DgIPKHnb/Cjlf63pmZT5Qs7/K0p/zkyijHUFqaEY7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}