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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '678a586967856212134fcc9a960ff01285e7e6802b0578904cef280f23e1d03e' 
  AND token = 'phmmH0kLSqLqOPkhLVLm03sshed7gkMw8KjN4Vi8pdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}