SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8acffdf651b39f1806df4f40d75f7bd4593b1544ce17657319654aa930704b7f' 
  AND token = 'jp+A+GY42DypzuyB6rL4qO7D6AZpjd16OsLBGnH5S1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}