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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e987a25764938f3ffb328a5ea466a4c059109d3a110e97fa7d1094ab2a288f35' 
  AND token = 'P66piEF6T1AP6s80Rze33vaHlOqK8qyMrhA+LyF2F+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}