SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec00ade3601173d53455bd02ea5131e50acdb8964f28b1158f3fe50a324dcc1' 
  AND token = 'GM4cjfChVxIig0T0uk4xakhvCz+HX1xzhcbRUWJPuVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}