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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc589f6bb631e56d0f72f0019987a7c610780777349aa100942ffe97f0ca66f' 
  AND token = 'd/0+Kf/nwA2vf38pjPTF+z+4c7M3F8m1ya2+vGnuloc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}