SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d50bf7650333fd6312deb50bbbd610dc9f78a1540224bca8f8bfde1779105d2' 
  AND token = 'mtg5G0qJ9K9AUYkQa7W8bPThEaZM/ME3f0Z6evTuRNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}