SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8bada10b82d9b4a97bb2c3b53290838e1982e049e6020dc00c0b258a7109e6' 
  AND token = 'wTZNGEm+gDJ4W9/U/dlQfpZZrfySgRT0zU2XmAhlv7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}