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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '156a22150243bef0aad1837e095cf754b46cf90b47ad120a51101f38b47787e7' 
  AND token = 'dyKoE9zq5X1aCNQEiPuB8+yip9UZspmxohjq3ivdWPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}