SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e3575150ebf1f06bb5997aaeb65059f058ba95e78e50724c73cd7f6bb892244' 
  AND token = 'dOCKxwcfpw8uZ0ipYQsZALR5efn2dS7Gz/5cOrDQmsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}