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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e429600ecb9be96291942131521f0f3b64533d1efdc0ff773b2de9d3b8b7633' 
  AND token = 'LfFtUHgwdjWw0/bTCyf1zYC4eSDm68VMyjKPAlyj6Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}