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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb76c4296b62e93816737561d43b52ee297c08a51a09ee5cffbb622e59e3a53' 
  AND token = 'SCe0+Vl12+51lKELQllUKcp9YFXb/aJ1ENzE/iESaJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}