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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b88ebce0b91df52e0c78005b289c8ffda0c31f9f473ad9f7c08dc3b108416c55' 
  AND token = 'sfSqPFX8QMwnyQAafacUgu3SDRj5pVBmL8cnBjzZ0qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}