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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75718a0e45822629ba2d31d141738d8c36a424d1eefec97a2e7b67c25d762ca4' 
  AND token = 'SQTvU49Z2MmQ4SzpRqG4E5bztK0mJesn18Zu2XxoYNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}