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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014fb2333ddd0926dc762451e45eb39ab59c2e79d878f36168661a6beebd8f55' 
  AND token = '4Uajv8Z5gQ9Mq0smicGgfb61gEv+6kOs4tsBlLfSNzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}