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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e7ef2e1c6d4725a73459a57e9801eb24bc115313950d0434dc9c140eeae5cf' 
  AND token = 'sL0mpW75DpjS4vUx1FR/NiGxgab0Lc7JbbyywOJicqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}