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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21b4ccd7d0dbd1ed568ec46d8856758e596d9a27aa5a9eda05ac80ee430763cb' 
  AND token = '9ZSxA5j0NLZG/Ylpez8IQR5CyXdfpQnjBTiyE2zw0CA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}