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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f2bb117bea7bc4496a9763079a7253a895c6caa269e8bcc6f72529a14b98427' 
  AND token = 'WAy0ObeVmIXxinGRlXCMSag1SPnIp5V1svNTmYlXcPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}