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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65c528440f770f1cdec7e8d45cc751d114d5c083db1e2c1676c9b28db8398081' 
  AND token = 'SwdKo7Q0ZP2AmDQ5xffCU7/qPsavnI6+hNMPHacWtqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}