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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8050c9c36ac9ac6286f17af3d5d3ad49a9232399dd86ed58c1a3a623a951c3c' 
  AND token = 'zZ9Nkkj+64ATPhOoAs/gajKoa+uiwWq+BoRPh8xhuPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}