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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f66f221c4c2e77f39c2d21a86a30efe86754c04d591d9a9468eff05367bbca73' 
  AND token = 'EsncmmA9rW23I7Wbc8saNGJr6hyD7Nq+8kg8cpZMXfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}