SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0223f85b85f2db8d00890803a77c34a40bbf5020a3e09a2b322c66816a225fbd' 
  AND token = 'G/W6LcTGtBKir15W5KGhLMQFTLQrc9TuqWGUl+CUkow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}