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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861f7a7b4d3767dab68ee47ecd6afda831559ade7da3692e344471a78b1b37f9' 
  AND token = 'NlE+WRrSn54aUCx+eVPAav+FC3Ig4NYOI2a0oSMyGzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}