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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e4c0d2428fd23f433d5459717d1ec10307fd8bc1326969949f5358cdff2b53' 
  AND token = 'NoUnzYG6V7NC/QkPmdZ419geNEBVykUoXoZREWCa0a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}