SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f76f9d1c52a79d816751ae1d17e37a0f836f7d35fd22733e7460718de0648d9f' 
  AND token = '+Cy9ZzHIzVWg2ajXDmKjfSS+UK/HjIzZSGE97aWT9VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}