SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c8e9fb429d3b6c6e34b9400d07a76aa68d77eb183958c530ac415d89ebf7c1' 
  AND token = 'Cl+5IlHzF3GlGzQIHMdpIrD64g7C1JnG7ceRNcgNwpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}