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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f099a950c386adf9950e619fc522a0ca4b691d9555f145458d59d585e60ec7' 
  AND token = 'Iqn6VbE5SOpuIJXkO7t5oL7h7IXdUUzaSX3V5wcoLFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}