SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '383547584bdad0582c0020e3509d6f87212d8b9b20d67e397bba4a9872b85d87' 
  AND token = 'RgF4i+9ELhnE+EZJgIhAgrQO4lSJ2FffyJMssBYL+KI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}