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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387d87eef5a7d6653e923ae9d82326d00a5bffa5085ca0f363390997e95f1165' 
  AND token = 'PJdO2fzC64YNaksPmkr0z/Q+k5tIbjxbYhTBfWVT2RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}