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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8500083dc5595d2f81a013f2fe5784d0e28d22ff6e07c575b094068f694e502c' 
  AND token = 'dMuE6vI5U9o6hwxzkmzaDEVf4PTSyX06KRzZuF+gAZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}