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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f63286abb37f611677c847f6d3526c926166f42977b1d9d0e04b8216cf7d53' 
  AND token = 'm0iZDfZfbySiopFXlsxWwbCvpJ/jkW4dzfDEiZQ6XmU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}