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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68993804421fcc7409a7d88d5f800c09f8d82391745a2af919fc01295dee5815' 
  AND token = 'lAzYMw3ZUxuOLlxgHTY+Fc50t4aRs9E1gAblMEVCgPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}