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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2378744a04742c0ad0408d5d9e6c4c4e4b1ed6caf5ccbf959a536e33b784e42' 
  AND token = '5EdaSOK545Xb8KXXIRQj7oFCMnqDb/SUgceGKBCVct0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}