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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80e039ad932b9506fc6a868f9fb754a2ffb9b4ff44daacd61f3268b86fbeb3d' 
  AND token = 'hK29fymp/7qEm6iDnQotfo9rgRdXRvBu+w9cG1CBcgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}